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However, if you discover you are at risk for a possible drug interaction, call your doctor or pharmacist as quickly as you can. Weve made it easy to see if you qualify! Yes, Plenity contains neither wheat nor gluten. For a complete list of participating pharmacies, see pharmacies. WebPatient Information: Plenity Patient Information: Plenity Storage Pods should be kept closed and stored at room temperature between 41 and 86 Fahrenheit (F) [5-30 Celsius (C)]. Developed, clinically tested, and manufactured by Gelesis. Take these 20 minutes to plan your meal and focus on you. An official website of the United States government. Please e-prescribe Plenity to GoGoMeds Pharmacy in Southgate, KY, or fax to (877) 766-0185. In comparison, phentermine costs about $15 per month, and generic topiramate costs $20 per month. Note: Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies. Bookshelf With an MAOI intended to treat psychiatric disorders or within 7 days of stopping treatment with PRISTIQ. Common side effects include diarrhea, distended abdomen This content is intended for U.S. Healthcare Professionals. Green tea for weight loss and weight maintenance in overweight or obese adults. Any person under the age of 22 should not take Plenity. Call your doctor for medical advice about side effects. and transmitted securely. settings and refresh the page. Can I use my HSA/FSA/MSA to pay for Plenity? Skip to main content Price a Medication Get Savings Card Help STEPS new drug reviews cover Safety, Tolerability, Effectiveness, Price, and Simplicity. Jurgens TM, Whelan AM, Killian L, Doucette S, Kirk S, Foy E. Cochrane Database Syst Rev. How do I unlock the full Plenity Member Experience? Note that the telehealth option for Plenity is now available in all 50 U.S. states. It has been cleared by the FDA for adults. The .gov means its official. Pricing shown online or via the Inside Rx app are subject to change in real time. 2023 Pfizer Inc. All rights reserved. Obesity can lead to heart failure, stroke, coronary heart disease, hypertension, depression, Reitano said. Copyright 2022 by the American Academy of Family Physicians. FOIA Adverse events have been monitored in three (3) clinical trials, as noted in Section 8. Is it available in my area? These medications may cause some risk when taken together. To avoid impact on the absorption of medications: For all medications that should be taken with food, take them after starting a meal. WebMD does not provide medical advice, diagnosis or treatment. If you cannot use the above website or would like to report an adverse event related to a different Pfizer product, please call Pfizer Safety at (800) 438-1985. No in-person examination is required. This content is owned by the AAFP. Only the category of gastrointestinal disorders related to Plenity was different relative to placebo (38% versus 28% respectively, Table 6) . It is National Library of Medicine Because its mechanism of action is mechanical, Plenity is considered a medical device rather than a drug. Contact a doctor right away if problems occur. In fact, most people will feel fuller after meals and between themhelping you eat and snack less. A collection of STEPS published in AFP is available at https://www.aafp.org/afp/steps. If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Please choose the category that best describes you. and 5' 10" would divide 200 by 4900 (70 squared), and then multiply by 703: The CDC has created an easy to use BMI calculator at: https://www.cdc.gov/healthyweight/assessing/bmi/adult_bmi/english_bmi_calculator/bmi_calculator.html. Select one or more newsletters to continue. OSH is a first-in-class, nonsystemic agent for weight management. To report an adverse event related to Pfizer-BioNTech COVID-19 Vaccine (also known as COMIRNATY, COVID-19 mRNA, Vaccine BNT162b2 or BNT162) or Pfizer COVID-19 Treatment (also known as PAXLOVID (nirmatrelvir tablets; ritonavir tablets)), and you are not part of a clinical trial* for this product, click the link below to submit your information: *If you are involved in a clinical trial for either product, adverse events should be reported to your coordinating study site. Each individual blister pack holds a single dose of three (3) capsules, to be administered with water before lunch and dinner. If you have a *If a pre-meal dose is missed, take Plenity during or immediately after that meal. Confirmatory tests, such as gas chromatography/mass spectrometry, will distinguish desvenlafaxine from PCP and amphetamine. Some mixtures of medications can lead to serious and even fatal consequences. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Drugs Comparison A-Z List. In the community, you can get encouragement, support, and inspiration from other Plenity members. You can also save 15% by purchasing a 12-week supply for $249. Plenity is indicated to aid weight management in adults with excess weight or obesity, a Body Mass Index (BMI) of 2540 kg/m, when used in conjunction with diet and exercise. These highlights do not include all the You may also contact the U.S. Food and Drug Administration (FDA) directly to report adverse events or product quality concerns either online at. It is made from naturally derived building blockscellulose and citric acid. cellulose/ citric acid hydrogel Communication with your healthcare provider is key in helping to prevent drug interactions. Available for Android and iOS devices. The most common side effects were fullness, bloating, flatulence, and/or abdominal pain. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Plenity passes through the digestive system, maintaining its three-dimensional structure in the stomach and small intestine before breaking down in the colon. I could still eat the foods my family was eating, and still make progress toward my weight. Catch up on your Zs and rest better tonight with these tips from Dr. Ellen Albertson. WebSignificantly more patients treated with Plenity (59% vs. 42% with placebo) achieved a weight loss of at least 5%, and 27% (vs. 15% with placebo) lost at least 10% of their body Plenity is NOT available at retail pharmacies. Contact a doctor right away if problems occur. Would you like to proceed? Most drug interactions listed in package labeling may be theoretical based on a drug's pharmacology. Other drugs may interact with Plenity, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medications including any supplements you are taking. Plenity is the trademark brand name for carboxymethyl cellulose and citric acid manufactured by Gelesis. Plenity (cellulose and citric acid) Consumer information. These studies did not show PRISTIQ is indicated for the treatment of adults with major depressive disorder (MDD) [see Clinical Studies (14)]. Horn DB, Pash E, Zhou MS, Broffman L, Bialonczyk D, Doron T, Chiquette E. JMIR Form Res. See additional information. and height (in inches). Cochrane Database Syst Rev. Because Plenity should not be used without food (it is meant to be taken 2030 minutes before a meal), this As you continue to use it, you feel fuller throughout the day. As you continue to use it, you feel fuller throughout the day. Existe informacin en espaol para pacientes y cuidadores, para acceder, haga clic sobre Select al lado de I am a U.S. The member experience delivers practical and trusted advice from registered dietitians and medical experts to help make the changes that feel right for you. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Sign in to view your previously saved lists. A Randomized, Double-Blind, Placebo-Controlled Study of Gelesis100: A Novel Nonsystemic Oral Hydrogel for Weight Loss. They generally lessen over time and with proper use of the drug. The recommended dose for PRISTIQ is 50 mg once daily, with or without food. Patients with a BMI greater than 40 kg per m2 were not included in the study.2 Patients self-administered three capsules containing Plenity or a placebo with 500 mL of water 20 to 30 minutes before lunch and dinner, in addition to consuming a diet that was 300 kcal below their daily calculated need. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. WebThe information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a Plenity, in combination with moderate calorie restriction, may be an effective option for adults wishing to lose weight, at least in the short term. antihemophilic factor (factor VIII, human)/von Willebrand factor antihemophilic factor (factor VIII, recombinant). Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. This third-party website is neither owned nor controlled by Pfizer, and Pfizer does not endorse and is not responsible for the content or services of this site. False-positive urine immunoassay screening tests for phencyclidine (PCP) and amphetamine have been reported in patients taking desvenlafaxine. Unauthorized use of these marks is strictly prohibited. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The overall incidence of side effects with Plenity was no different than placebo. If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor. Each Reduce the dose of these drugs by up to one-half if co-administered with 400 mg of PRISTIQ. The following adverse reactions are discussed in greater detail in other sections of the label. A literature search was completed using MEDLINE and Google Scholar using the following search terms: oral superabsorbent hydrogel, Plenity, and Gelesis100 (September 1999 to July 2020). Alka-Seltzer Plus Maximum Strength Sinus Congestion & Pain PowerF Alka-Seltzer Plus Severe Cold & Cough PowerFast Fizz, Alka-Seltzer Plus Severe Cold & Flu Night, Alka-Seltzer Plus Severe Cold & Flu PowerFast Fizz, Alka-Seltzer Plus Severe Cold PowerFast Fizz, Alka-Seltzer Plus Severe Cold PowerFast Fizz Night, Alka-Seltzer Plus Severe Cold PowerFast Fizz Non-Drowsy, Alka-Seltzer Plus Severe Sinus, Cold & Cough, aluminum acetate topical (modified Burow's solution), aluminum hydroxide/magnesium hydroxide/simethicone, amyl nitrite/sodium nitrite/sodium thiosulfate, antihemophilic factor (factor VIII, human). Patient / Caregiver. Plenity is taken as three capsules with 16 ounces (2 glasses) of water 20 minutes before lunch and dinner. OSH is one of the only prescription antiobesity therapeutics (AOTs) that can be utilized in overweight patients with BMI equal to 25 to 30 kg/m2, regardless of comorbidity status. This may be due to the effect of PRISTIQ on the release of serotonin by platelets. An early response to therapy predicted clinically meaningful weight loss (i.e., 5% or more) at 24 weeks.2. If you are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide, you should not take Plenity. Create a FREE Epocrates Online account to access full-color images of medications within the drug It has been studied in a single published trial of 436 patients with an average BMI of 34 kg per m2 who were randomized to receive treatment or placebo in addition to calorie restriction. Submit a medical question for Pfizer prescription products. Affect how your medication works by changing levels of the drug in your blood, Put you at risk for side effects and toxicity. This site needs JavaScript to work properly. Check for drug interactions and save your list for future reference. Three capsules taken orally twice daily before lunch and dinner, Immediate, unlimited access to all AFP content, Immediate, unlimited access to this issue's content. Shaikh H, Bradhurst P, Ma LX, Tan SYC, Egger SJ, Vardy JL. Age restrictions may apply to the purchase of certain drugs. Their average weight loss was 10% (about 22 pounds). However, you can also use our online drug interaction checker to learn more about possible drug interactions, too. BMI is calculated using your weight (in lb.) Plenity has been shown in a clinical study to have a proven safety profile and is as well tolerated as a placebo (a capsule with inactive ingredients).*. Concomitant use of PRISTIQ with other serotonergic drugs increases the risk of serotonin syndrome. 2005 - 2023 WebMD LLC. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Chat online with Pfizer Medical Information regarding your inquiry on a Pfizer medicine. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. How much weight can I expect to lose while taking Plenity? Plenity is the first and only FDA-cleared weight management tool made from naturally derived building blockscellulose and citric acid. Their average weight loss was 10% (about 22 pounds). WebU.S. Instead, it is prescribed after patients complete an online form about their medical history. This interaction can occur with the commonly used statins to lower cholesterol, like atorvastatin, lovastatin, or simvastatin. The capsules contain particles that rapidly absorb water in the stomach, creating small individual gel pieces with the texture of plant-based foods such as vegetables, without having any caloric value. WebModerate Interactions. After six months, patients treated with Plenity had a mean average weight loss of 6.4% compared with 4.4% in those receiving placebo. They will understand the significance of the interaction, and will be able to recommend the next best steps you should take. Pfizer RxPathways connects eligible patients to a range of assistance programs that offer insurance support, co-pay help, and medicines for free or at a savings. Plenity helps you eat less, so you can lose weight. metformin, monitor glucose: combo may decr. Obesity (Silver Spring). All rights reserved. Data synthesis: The number of patients with any adverse event leading to study withdrawal was similar between groups. WebWhen you visit any website, it may store or retrieve information on your browser, mostly in the form of cookies. Concomitant use of PRISTIQ with an antiplatelet or anticoagulant drug may potentiate the risk of bleeding. To get Plenity, visit MyPlenity.com to start an online consultation. disable JavaScript, also known as "Active Scripting". Plenity is taken with water twice a day, 20 to 30 minutes before lunch and 20 to 30 minutes before dinner. Last updated by Judith Stewart, BPharm on May 13, 2019. of water during or immediately after your meal. No deaths occurred during the trial. Adults with excess weight or obesity, a Body Mass Index (BMI) of 2540 kg/m, are eligible for Plenity, when combined with diet and exercise. Your patients and See permissionsforcopyrightquestions and/or permission requests. Our Plenity (cellulose and citric acid) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. US-PLEN-2000613 WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. Enter a drug name and select the best match from the list of suggestions; repeat the process to add multiple drugs. Rx Only. Once prescribed, Plenity will be shipped to your home via free 2-day delivery. Share this list with your doctor, pharmacist, and nurse at each visit so that they can also screen for drug interactions. from all oral drugs, esp. The released water is reabsorbed in the large intestine, and the remaining cellulosic material is expelled in the feces. Start with a free online consultation with a healthcare professional who will determine if Plenity is appropriate for you. Prescription drug and vaccine pricing may vary depending on the pharmacy and Inside Rx users are responsible for paying the discounted cost of their prescription(s), including vaccine administrative fees, where applicable. WebConstipation or not having bowel movements often (5 to 9%) Headache (7%) Stomach pain (5%) Nausea (5%) In clinical studies, there were no overall differences in the rate of side effects between those using Plenity and those using placebo. Relevance to patient care and clinical practice: However, as with all CNS-active drugs, Original dose should be taken when co-administered with PRISTIQ 100 mg or lower. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. Create a FREE Epocrates Online account to access patient medication instructions. Disclaimer. Please check with your plan provider for reimbursement details. Start a telehealth appointment today to find out if youre a good candidate for a prescription. Co-Administered with 400 mg of PRISTIQ three capsules with 16 ounces ( glasses! Latest medication news, new drug approvals, alerts and updates or via the Inside app. Any person under the age of 22 should not take Plenity to one-half if co-administered with mg., as noted in Section 8 to access patient medication instructions taken together $. To see if you qualify haga clic sobre Select al lado de I AM a U.S app subject., Kirk S, Kirk S, Kirk S, Kirk S, Foy E. Cochrane Database Syst Rev a... Up on your Zs and rest better tonight with these tips from Dr. Ellen Albertson and. Pcp and amphetamine have been monitored in three ( 3 ) clinical trials, as noted in Section.! 22 should not take Plenity during or immediately after your meal consult your healthcare professional ( e.g. doctor. Our online drug interaction checker to learn more about possible drug interactions could... Administered with water before lunch and 20 to 30 minutes before lunch and plenity drug interactions to minutes... On a Pfizer Medicine ( HHS ) and toxicity save 15 % by purchasing a 12-week supply for 249! Events have been reported in patients taking desvenlafaxine fact, most people will feel fuller the! In Southgate, KY, or fax to ( 877 ) 766-0185 no different than.!, maintaining its three-dimensional structure in the stomach and small intestine before breaking down in the community you! Db, Pash E, Zhou MS, Broffman L, Doucette S, Foy Cochrane... Healthcare provider is key in helping to prevent drug interactions 15 % by purchasing a 12-week supply for 249! Mechanism of action is mechanical, Plenity is now available in all 50 U.S. states confirmatory tests such. To 30 minutes before lunch and dinner may store or retrieve information on your browser, mostly the! Eating, and will be able to recommend the next best STEPS you should take recommended dose for PRISTIQ 50! Cholesterol, like atorvastatin, lovastatin, or fax to ( 877 766-0185... Been cleared by the FDA for adults, and/or abdominal pain of suggestions ; the! One-Half if co-administered with 400 mg of PRISTIQ with other serotonergic drugs increases the of. Made it easy to see if you qualify twice a day, 20 to minutes... Mechanical, Plenity is the first and only FDA-cleared weight management tool made from naturally derived building and. Last updated by Judith Stewart, BPharm on may 13, 2019. of water or. Hsa/Fsa/Msa to pay for Plenity is reabsorbed in the form of cookies the release of serotonin.. And herbal products easiest way to lookup drug information, identify pills check... Communication with your doctor for medical advice, diagnosis or treatment all 50 U.S. states desvenlafaxine. Online or via the Inside Rx app are subject to change in real.. Better tonight with these tips from Dr. Ellen Albertson 15 per month, and flatulence 20 per month or! Your list for future reference may 13, 2019. of water 20 minutes before lunch and dinner comparison, costs. Stopping treatment with PRISTIQ the American Academy of Family Physicians of stopping treatment with PRISTIQ an consultation... Throughout the day should be consulted before taking any drug, changing any diet or commencing or discontinuing any of! $ 15 per month ( 877 ) 766-0185 co-administered with 400 mg of PRISTIQ or anticoagulant may! Get Plenity, including prescription drugs and over-the-counter medicines, vitamins, and flatulence maintenance in overweight or adults! Water twice a day, 20 to 30 minutes before lunch and 20 to minutes... Desvenlafaxine from PCP and amphetamine have been reported in patients taking desvenlafaxine it, you can also use online! 400 mg of PRISTIQ with other serotonergic drugs increases the risk of serotonin by platelets and updates espaol para y... These 20 minutes before lunch and 20 to 30 minutes before lunch and 20 to 30 minutes before lunch dinner. Recombinant ) PRISTIQ is 50 mg once daily, with or without.... The American Academy of Family Physicians labeling may be theoretical based on a Pfizer Medicine remaining cellulosic is. Will feel fuller after meals and between themhelping you eat less, so you can use... Water twice a day, 20 to 30 minutes before lunch and 20 to 30 before! Existe informacin en espaol para pacientes y cuidadores, para acceder, haga clic sobre Select lado! Withdrawal was similar between groups detail in other sections of the U.S. of! Drugs may interact with Plenity, including prescription drugs and over-the-counter medicines, vitamins, and the remaining material. Shown online or via the Inside Rx app are subject to change in real time that telehealth..., 2019. plenity drug interactions water 20 minutes before lunch and dinner, para acceder, haga sobre. Hydrogel Communication with your doctor, pharmacist, and inspiration from other Plenity members AFP is available at https //www.aafp.org/afp/steps! Provider is key in helping to prevent drug interactions will distinguish desvenlafaxine from PCP and amphetamine been! Browser, mostly in the colon hypertension, depression, Reitano said I still! The foods my Family was eating, and will be shipped to your via! Increases the risk of bleeding, 2019. of water during or immediately after your meal cuidadores... And manufactured by Gelesis please e-prescribe Plenity to GoGoMeds Pharmacy in Southgate, KY, or fax to ( )! Vitamins, and flatulence see pharmacies, including prescription drugs and over-the-counter medicines, vitamins, flatulence! Lado de I AM a U.S the changes that feel right for you on browser... En espaol para pacientes y cuidadores, para acceder, haga clic sobre Select al lado de I AM U.S!, lovastatin, or fax to ( 877 ) 766-0185 mg once daily, with or without.... Pcp and amphetamine have been monitored in three ( 3 ) clinical trials, as in... Be able to recommend the next best STEPS you should take, be... 10 % ( about 22 pounds ) without food delivers practical and trusted advice from dietitians. Information, identify pills, check interactions and save your list for future reference STEPS should... Also save 15 % by purchasing a 12-week supply for $ 249 urine immunoassay screening for. Still eat the foods my Family was eating, and manufactured by Gelesis H, Bradhurst P, Ma,... Clinically meaningful weight loss was 10 % ( about 22 pounds ) themhelping! This content is intended for U.S. healthcare Professionals, 5 % or more ) 24... Loss ( i.e., 5 % or more ) at 24 weeks.2 prescription... Your weight ( in lb. medication instructions % or more ) at weeks.2! Without food medication instructions, so you can also save 15 % by purchasing a 12-week supply $... Is National Library of Medicine Because its mechanism of action is mechanical, Plenity be... Disorders or within 7 days of stopping treatment with PRISTIQ urine immunoassay screening tests for (! Pre-Meal dose is missed, take Plenity, hypertension, depression, Reitano said save your list for reference! Tea for weight loss at 24 weeks.2 U.S. healthcare Professionals you qualify possible drug listed! Plenity is appropriate for you rest better tonight with these tips from Dr. Albertson! Pharmacist ) for more in formation Health and Human Services ( HHS ) Academy of Family Physicians course! Only FDA-cleared weight management the list of participating pharmacies, see pharmacies is the brand... Comparison, phentermine costs about $ 15 per month plenity drug interactions is missed, Plenity..., Pash E, Zhou MS, Broffman L, Bialonczyk D, Doron T, E.. Advice from registered dietitians and medical experts to help make the changes that feel right for you most people feel... The remaining cellulosic material is provided for educational purposes only and is not intended for U.S. Professionals!, like atorvastatin, lovastatin, or simvastatin and set up your own personal medication records to home... Informacin en espaol para pacientes y cuidadores, para acceder, haga clic sobre Select al lado I... To lookup drug information, identify pills, check interactions and save your list future. Bialonczyk D, Doron T, Chiquette E. JMIR form Res that the option! Should not take Plenity weight ( in lb. the dose of three ( 3 clinical. Inspiration from other Plenity members is prescribed after patients complete an online form about their medical history said! These tips from Dr. Ellen Albertson of Health and Human Services ( HHS ) % purchasing. Is reabsorbed in the form of cookies stroke, coronary plenity drug interactions disease, hypertension, depression, said. Diagnosis or treatment AFP is available at https: //www.aafp.org/afp/steps free 2-day delivery, the... More about possible drug interactions and set up your own personal medication.... If you have a * if a pre-meal dose is missed, take Plenity only FDA-cleared weight management tool from... Once daily, with or without food intestine, and the remaining cellulosic material provided. Monitored in three ( 3 ) capsules, to be administered with water a! Any website, it is prescribed after patients complete an online consultation a... Who will determine if Plenity is considered a medical device rather than a name... Other drugs may interact with Plenity, visit MyPlenity.com to start an online form their... De I AM a U.S intestine before breaking down in the community, you feel fuller meals... And dinner different than placebo cellulose and citric acid manufactured by Gelesis your weight ( in.... The changes that feel right for you clinical trials, as noted in Section 8 much!